A DWARF MUTATION IN PORTULACA SHOWING VEGETATIVE REVERSIONS

A Dwarf Mutation in Portulaca Showing Vegetative Reversions.

I n 1914 Mr. B. T. AVERY, who was then my gardener assistant a t the CONNECTICUT AGRICULTURAL COLLEGE, called my attention to a single dwarf individual in a bed of red-flowered plants from commercial seed of a variety of Portulaca grandijora. This plant formed a low compact pin-cushion-like growth in striking contrast to the long straggling habit of the normal plants near it. It is the origin o...

Vegetative Reproduction Potential of Common Purslane (Portulaca oleracea)

A Dwarf Mutation in the Rabbit

An hereditary type of dwarfism in the rabbit has been described. In contrast to the dwarfs described in other animals, this type is evident at birth and conforms to the classification, nannosomia primordialis, as used in human pathology. In homozygous form the variation is lethal and produces a miniature individual approximately one-third the size of its normal sibs. Heterozygous animals are ap...

The sequence spectrum of frameshift reversions obtained with a novel adaptive mutation assay in Saccharomyces cerevisiae

Research on the mechanisms of adaptive mutagenesis in resting, i.e. non-replicating cells relies on appropriate mutation assays. Here we provide a novel procedure for the detection of frameshift-reverting mutations in yeast. Proliferation of non-reverted cells in this assay is suppressed by the lack of a fermentable carbon source. The test allele was constructed in a way that the reversions mim...

A frameshift mutation in MC1R and a high frequency of somatic reversions cause black spotting in pigs.

Black spotting on a red or white background in pigs is determined by the E(P) allele at the MC1R/Extension locus. A previous comparison of partial MC1R sequences revealed that E(P) shares a missense mutation (D121N) with the E(D2) allele for dominant black color. Sequence analysis of the entire coding region now reveals a second mutation in the form of a 2-bp insertion at codon 23 (nt67insCC). ...